Posted by

A new, ongoing feature of this blog will be Skincare Goal Spotlights. I’ll take a specific goal of a skincare routine and do a deep dive into what’s happening in your skin and how to achieve that goal. This week: aging!

Your skin’s structure

Before I get into it, let’s do a real quick biology lesson. Your skin has three layers: the epidermis (the really thin, outermost layer); the dermis (a thicker layer below that); and the hypodermis (a fat-storing layer that links the skin to the tissues below). In terms of skincare and aging, we mostly care about the epidermis and dermis.


In the dermis, see that orange-tan stuff that the blue dots are floating in? That’s called the dermal extracellular matrix. It’s basically the scaffolding that holds the shape of your skin in place, and gives it its firmness and ability to bounce back. It’s a gel-like structure made of collagen, elastin, and glycosaminoglycans (like hyaluronic acid).

The biology of aging

Because of that matrix, your dermis is crucial in maintaining the plumpness and bounce of youthful skin. As it degrades over time, you start seeing the sagging, droopy skin associated with aging. The epidermis is also important in aging; it dries out over time, losing both lipid and water content, giving older skin that papery quality.

Scientists aren’t 100% sure what causes wrinkles, but it probably comes partly from a breakdown in the bond between the dermis and the epidermis. As they start to break away from each other, rifts form and become wrinkles.

Extrinsic vs. intrinsic aging

There are two types of factors at play with skin aging: extrinsic (external/environmental) and intrinsic (from within your body).

The number 1 extrinsic factor is sun exposure. UV radiation has a serious effect on the skin; beyond the risk of melanoma, UV radiation degrades your dermal collagen and prevents new collagen synthesis. Other extrinsic factors, like smoking and air pollution, have a similar effect. Extrinsic factors cause a lot of damage, but the good news is that we have a lot of control over them (wear sunscreen and don’t smoke, basically).

Intrinsic factors are a different story; these are just natural things that happen in our body as we get older. A lot of this is due to decreasing levels of sex hormones – for women, a lot of skin aging takes place after menopause – but also comes from general wear and tear of living and getting older.

Some of the ways skin changes naturally as you get older include:

  • Skin gets thinner as cell turnover decreases – epidermis loses about 6.4% thickness every decade
  • Skin gets drier – sebum production decreases by up to 60%, and water content decreases dramatically (partially due to less hyaluronic acid in the epidermis)
  • Skin barrier integrity decreases, meaning it’s slower to repair itself
  • Collagen and elastin levels in the dermis decrease
  • Production of collagen and elastin slows

The aging caused by extrinsic factors actually looks different than intrinsic aging. Extrinsic factors like sun exposure lead to coarse wrinkles, sun spots, and thick, leathery-looking skin, while natural intrinsic factors cause fine wrinkles, increased laxity, and pale, delicate-looking skin.

How to prevent the signs of aging

You can only truly prevent those extrinsic factors. Always, always wear sunscreen! On average, UV damage is responsible for 80% of the signs of aging. If you want to see how dramatic it can be, here’s a photo of a man who drove a delivery truck for 28 years and so only had UV exposure through his driver’s side window:


Smoking causes similar damage – check out these side-by-sides of identical twins where only one twin smokes.

How to treat the signs of aging

You may not be able to prevent all signs of aging, but you can mitigate it quite a bit. The four main factors in the appearance of aging skin are:

  • Less collagen
  • Less elastin
  • Drier skin
  • Thinner skin

Good news: of those four, there’s only one we have zero control over. Scientists haven’t found any way to increase elastin production, so as that stuff starts to break down, it’s just gone. We can treat the other three, though!

Make more collagen

Through both natural aging and environmental damage, your dermis starts producing less collagen, but a few different ingredients can actually stimulate new collagen production in your dermis. Those ingredients are:

  • Retinoids (these can also fade pigmentation spots, another sign of aging)
  • Vitamin C (only L-ascorbic acid and magnesium ascorbyl phosphate can increase collagen production in a meaningful way; sodium ascorbyl phosphate’s not gonna help much)
  • Glycolic acid
  • Peptides

Keep the collagen you have

Your dermal collagen also breaks down over time, both naturally and due to UV radiation. Anti-oxidants scavenge the free radicals that cause that breakdown and help protect your collagen from damage. Those scavengers include:

  • Vitamin C
  • Vitamin E
  • Niacinamide (it regulates cell metabolism and regeneration, and can also increase skin elasticity and fade pigmentation spots)
  • Polyphenols

Keep your skin from thinning

Certain ingredients can increase the thickness of your stratum corneum and improve your skin’s barrier and moisture retention abilities, while keeping your skin from getting that pale, translucent quality associated with aging. Those ingredients include:

  • AHAs like glycolic acid
  • Retinoids
  • Niacinamide
  • Conjugated linoleic acid

Treat dry skin

There’s not much you can do to prevent your skin from drying out over time, but keeping a strong, moisture- and lipid-based skincare routine can keep your skin plump, hydrated, and radiant. Look for products with ingredients like:

  • Hyaluronic acid
  • Ceramides and cholesterol
  • Plant oils high in linoleic acid

The power lifters in anti-aging

If you look at the ingredients I mentioned above, there are four that keep appearing: vitamin C, niacinamide, retinoids, and glycolic acid. A strong anti-aging routine will include all four of those. Here are some great products that feature those ingredients:

  • Pocketderm/Curology’s Anti-Aging formula: in my opinion, this is the best affordable anti-aging product on the market. It features vitamin C, niacinamide, and a form of retinoid called tretinoin. I’ve seen great results from it. It’s $19.99 a month, and that includes unlimited e-consultations with a dermatologist. (If you want to try it out, use this link to get your first month free.)
  • Cerave PM: my all-time favorite moisturizing cream. It features 4% niacinamide (an ingredient that works best in concentrations of 2-5%), plus ceramides, cholesterol, and a whole host of great moisturizing ingredients. I use it morning and evening.
  • Cosrx AHA 7 Whitehead Power Liquid: glycolic acid can be a pretty harsh exfoliant, so it isn’t for everyone, but this product is a great starter.
  • DIY Vitamin C: I’d already been feeling disenchanted with the sticky, quick-to-oxidize vitamin C serums I’d been using when I read Holy Snail’s eye-opening blog post about vitamin C. I’ve been making my own for a few months now and I’ll never go back. (Correction: I’ll go back when I get rich enough to afford a constant supply of Skinceuticals CE Ferulic, which is amazing and also $120 an ounce.) I’ll post my recipe soon. If you want to buy ready-made serums, a lot of people like OST C20 (although I personally couldn’t stand how sticky it was) or Paula’s Choice C15 Super Booster.
  • SUNSCREEN SUNSCREEN SUNSCREEN: Always, every day, no excuses. Japanese sunscreens really have the market cornered in terms of fast-absorbing, non-greasy, extremely effective products without a white cast. I’m desperately in love with Shiseido Senka Mineral Water UV Essence. (It’s called Aging Care on Amazon for some reason.)

When should I start this routine?

Honestly, you can start focusing on anti-aging whenever you want. So much of anti-aging is about preserving the skin you have that it’s pretty much always easier to start young. I started noticing my own fine lines when I was 25 or 26, so that might be a good age to start.

I want to end this post with an important message, though: there’s nothing bad about aging! Your skin naturally goes through a lot of changes throughout your life, and those wrinkles are a testament to your wisdom and experience. If you want bouncy, youthful skin, great! If you want to wear your wrinkles and spots as badges of a life well lived, awesome. Personally, I try to avoid the outside of my eyes during my anti-aging routine, because I really love my budding crows’ feet. They remind me how much I’ve laughed in my life. I hope they get enormous.

Sources: 1, 2, 3, 4, 5, 6, 7, 8, 9


  1. Great attitude about crinkles from smiling 😆 I’m throwing almost every one of the tools you mentioned at my skin and hoping for the best. Have you seen big changes from PocketDerm? –Angela

    1. The changes I’ve seen from Pocketderm have been slow but significant. It’ll be at least 6 weeks before you see any changes from tretinoin, but I’ve seen smoother, more even skin, less noticeable sebaceous filaments, and plumper, bouncier skin overall. I definitely recommend it!

  2. This post is amazing! I love all the knowledge you impart in your posts. And damn, between you and Fiddy, I’m going to have to get on the Cureology bandwagon soon (tho, recovering from a super rookie over-exfoliating mistake right now. oops).

  3. This is so helpful, nice to see all the ingredients for anti aging at once and what is for what )) I know which ingredients I’m missing and need to include into my skincare routine

  4. Love the post! I notice that some people start noticing the signs of aging early but take late action to treat it. Vitamin E really need to be considered since it can help inactive free radicals. It is good for sun protection too.

  5. Thank you for the great article. Now I know what ingredient to especially look out for. thank you, I’m so glad I started stealing and using my mom anti-aging cream when I was in my 19 .

  6. I make a product I call rewind serum that is identical to CE Ferulic and we sell it for like $40 at my pharmacy. It’s all pharmaceutical grade ingredients and I make it at a pH of 3.5 I believe. I sent some of the CE Ferulic to this company we get our chemicals from and these two cosmetic chemists from Brazil helped me develop a formula and tweaked it several times. It’s good stuff. I finally found a bottle to put it in so it doesn’t oxidize.

  7. love this blog, I definitely will quote some from you! (can I? haha)
    it summarizes different concepts in a super pretty way!

Leave a Reply to Mario - sunflowerdermatology.comCancel reply